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Case Review |
Clinical
Photograph of The Week |
A 30-year old female presented with sudden onset of
respiratory distress. She was earlier seen 12 months prior to
presentation, having been referred for panendoscopy following a
histological diagnosis of metastatic thyroid carcinoma from a cervical
lymphadenectomy specimen biopsied by a general surgeon. Panendoscopy
revealed a posterior tracheal bulge that was biopsied, and again reported
as metastatic carcinoma of throid. She was sent to oncologist for further
treatment but defaulted before presenting in acute respiratory distress.
Clinical finding revealed the features on this picture.
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What is the Best Management Option? |

1. 16th Annual oto-rhino-laryngological society of Nigeria (ORLSON) General Meeting
& Scientific Conference; November 22nd - 25th, 2006; Kaduna, Nigeria
2.
25th Alexandria Combined ORL Congress, April 18 - 20 2007; Alexandria, Egypt.
Deadline for Abstract submission January 15, 2007. Click
HERE for Details

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Should routine nasopharyngeal biopsy be made even when no tumour was
found during flexible endoscopy or EUA in a patient with isolated
serous otitis media? This study from Dublin (Glyn F et al,
J Laryngol Otol. 2006 Jun;120(6):439-41
) believed biopsy should only be done when tumour was found during
nasopharyngeal examination. Abstract:
Nasopharyngeal malignancy accounts for less than 2 per cent of all head
and neck cancers. Serous otitis media (SOM) causing deafness is a
recognized indicator of nasopharyngeal obstruction and the possibility
of a nasopharyngeal malignancy must be considered in all adults.
Examination under anaesthesia (EUA) and biopsy of the nasopharynx is
routinely undertaken in many centres to rule out nasopharyngeal
malignancy in adults with SOM. The purpose of this 10-year
retrospective study was to evaluate the case records of all adult cases
of SOM, including their presentation, clinical findings, management and
nasopharyngeal biopsy results. Eighty-five patients were included in
the study. Fifty-nine presented with unilateral SOM and 26 with
bilateral SOM. The primary presenting complaint in all cases was
hearing loss. A nasopharyngeal mass was documented in 55 patients (69
per cent). Four nasopharyngeal masses were noted to have irregular or
exophytic mucosa on flexible nasendoscopy. All patients underwent a EUA
of the ears and a nasopharyngeal biopsy. The four patients with
suspicious-looking masses were all found to have malignancies (two
squamous cell carcinomas, one B-cell non-Hodgkin lymphoma and one
adenocarcinoma). Three of these patients presented with unilateral SOM
and one with bilateral SOM. All other patients with masses were found
to have benign lymphoid hyperplasia. In total, 4.7 per cent of the
adults with conductive hearing loss secondary to SOM were found to have
a malignancy on nasopharyngeal biopsy. We would advocate a high index
of suspicion of a nasopharyngeal tumour in adults presenting with SOM.
If a mass is found in the nasopharynx then it should be biopsied. If no
mass is found then it is not necessary to biopsy; however, close follow
up, with repeat fibre-optic nasendoscopy, is advised. |
Journal Watch :Distant
Metastasis from Nasopharyngeal Carcinoma in Nairobi, Gacani et al, 2001
1. DODA
2006, capable of advanced hearing measure, and also paediatric hearing
assessment is being developed. If you requested for and got a free copy of DODA,
you may also look out for this latest version dubbed DODA-i, as well as for an
additional page on outcome of hearing assessment using DODA.
2. A subweb of this site, dedicated to online
publications of otorhinolaryngological grand round presentations across
Institutions all over Africa will soon take off. The subweb once active can be
accessed at http://www.otolaryngologyinafrica.net/grandround/ .
This page, is already active and you are enjoined to take
advantage of this to send in your grand round presentations. Also watch out for
online discussion forum for discussion of issues concerning otolaryngologists,
but not really of clinical nature at
http://otolaryngologyinafrica.net/discussionforum/
Till Next Week,
Biodun
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© Copyright Dr 'Biodun Olusesi, 2005 - 2006
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