Text Box: Abreast of Ear, Nose, Throat, Head & Neck Advances

Text Box: October 21, 2006

Text Box: Otorhinolaryngology News

Text Box: Inside This Issue
· LigStem Cells - Storms, Reality.?
· VC Palsy & Diagnostic workup.?
· TinAdult OME & NP Biopsy..? 
*     Case of the Week

 

 

 Case Review

 Clinical Photograph of The Week

A 30-year old female presented with sudden onset of respiratory distress. She was earlier seen 12 months prior to presentation, having been referred for panendoscopy following a histological diagnosis of metastatic thyroid carcinoma from a cervical lymphadenectomy specimen biopsied by a general surgeon. Panendoscopy revealed a posterior tracheal bulge that was biopsied, and again reported as metastatic carcinoma of throid. She was sent to oncologist for further treatment but defaulted before presenting in acute respiratory distress. Clinical finding revealed the features on this picture.

    

What is the Best Management Option?

1.   16th Annual oto-rhino-laryngological society of Nigeria (ORLSON) General Meeting & Scientific Conference; November 22nd - 25th, 2006; Kaduna, Nigeria

2.          25th Alexandria Combined ORL Congress, April 18 - 20 2007; Alexandria, Egypt. Deadline for Abstract submission January 15, 2007. Click HERE for Details

 
Should routine nasopharyngeal biopsy be made even when no tumour was found during flexible endoscopy or EUA in a patient with isolated serous otitis media? This study from Dublin (Glyn F et al, J Laryngol Otol. 2006 Jun;120(6):439-41 ) believed biopsy should only be done when tumour was found during nasopharyngeal examination.

Abstract: Nasopharyngeal malignancy accounts for less than 2 per cent of all head and neck cancers. Serous otitis media (SOM) causing deafness is a recognized indicator of nasopharyngeal obstruction and the possibility of a nasopharyngeal malignancy must be considered in all adults. Examination under anaesthesia (EUA) and biopsy of the nasopharynx is routinely undertaken in many centres to rule out nasopharyngeal malignancy in adults with SOM. The purpose of this 10-year retrospective study was to evaluate the case records of all adult cases of SOM, including their presentation, clinical findings, management and nasopharyngeal biopsy results. Eighty-five patients were included in the study. Fifty-nine presented with unilateral SOM and 26 with bilateral SOM. The primary presenting complaint in all cases was hearing loss. A nasopharyngeal mass was documented in 55 patients (69 per cent). Four nasopharyngeal masses were noted to have irregular or exophytic mucosa on flexible nasendoscopy. All patients underwent a EUA of the ears and a nasopharyngeal biopsy. The four patients with suspicious-looking masses were all found to have malignancies (two squamous cell carcinomas, one B-cell non-Hodgkin lymphoma and one adenocarcinoma). Three of these patients presented with unilateral SOM and one with bilateral SOM. All other patients with masses were found to have benign lymphoid hyperplasia. In total, 4.7 per cent of the adults with conductive hearing loss secondary to SOM were found to have a malignancy on nasopharyngeal biopsy. We would advocate a high index of suspicion of a nasopharyngeal tumour in adults presenting with SOM. If a mass is found in the nasopharynx then it should be biopsied. If no mass is found then it is not necessary to biopsy; however, close follow up, with repeat fibre-optic nasendoscopy, is advised.

 


     Journal Watch :Distant Metastasis from Nasopharyngeal Carcinoma in Nairobi, Gacani et al, 2001

 1.   DODA 2006, capable of advanced hearing measure, and also paediatric hearing assessment is being developed. If you requested for and got a free copy of DODA, you may also look out for this latest version dubbed DODA-i, as well as for an additional page on outcome of hearing assessment using DODA.

 2.  A subweb of this site, dedicated to online publications of otorhinolaryngological grand round presentations across Institutions all over Africa will soon take off. The subweb once active can be accessed at http://www.otolaryngologyinafrica.net/grandround/ . This page, is already active and you are enjoined to take advantage of this to send in your grand round presentations. Also watch out for online discussion forum for discussion of issues concerning otolaryngologists, but not really of clinical nature at http://otolaryngologyinafrica.net/discussionforum/ 

 Till Next Week,

 Biodun

 

 

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